MovDisordV3, Main, Exploration, bibRecord, 001E79

A recommended scale for cognitive screening in clinical trials of Parkinson's disease

Identifieur interne : 001E79 ( Main/Exploration ); précédent : 001E78; suivant : 001E80

A recommended scale for cognitive screening in clinical trials of Parkinson's disease

Auteurs : Kelvin L. Chou [États-Unis] ; Melissa M. Amick [États-Unis] ; Jason Brandt [États-Unis] ; Richard Camicioli [Canada] ; Karen Frei [États-Unis] ; Darren Gitelman [États-Unis] ; Jennifer Goldman [États-Unis] ; John Growdon [États-Unis] ; Howard I. Hurtig [États-Unis] ; Bonnie Levin [États-Unis] ; Irene Litvan [États-Unis] ; Laura Marsh [États-Unis] ; Tanya Simuni [États-Unis] ; Alexander I. Tröster [États-Unis] ; Ergun Y. Uc [États-Unis]

Source :

Movement Disorders [ 0885-3185 ] ; 2010-11-15.

RBID : ISTEX:40D88EA675753E232188B486DDBDA998C7C06B26

Descripteurs français

Pascal (Inist)
- Dépistage, Essai clinique, Maladie de Parkinson, Pathologie du système nerveux, Trouble cognitif.

English descriptors

KwdEn :
- Clinical Trials as Topic, Clinical trial, Cognition, Cognition Disorders (complications), Cognition Disorders (diagnosis), Cognition Disorders (psychology), Cognitive disorder, Humans, Medical screening, Nervous system diseases, Neuropsychological Tests, Parkinson Disease (complications), Parkinson Disease (psychology), Parkinson disease, Parkinson's disease, Psychometrics, Questionnaires, cognitive impairment, cognitive screening.
MESH :
- complications : Cognition Disorders, Parkinson Disease.
- diagnosis : Cognition Disorders.
- psychology : Cognition Disorders, Parkinson Disease.
- Clinical Trials as Topic, Cognition, Humans, Neuropsychological Tests, Psychometrics, Questionnaires.

Abstract

Cognitive impairment is common in Parkinson's disease (PD). There is a critical need for a brief, standard cognitive screening measure for use in PD trials whose primary focus is not on cognition. The Parkinson Study Group (PSG) Cognitive/Psychiatric Working Group formed a Task Force to make recommendations for a cognitive scale that could screen for dementia and mild cognitive impairment in clinical trials of PD where cognition is not the primary outcome. This Task Force conducted a systematic literature search for cognitive assessments previously used in a PD population. Scales were then evaluated for their appropriateness to screen for cognitive deficits in clinical trials, including brief administration time (<15 minutes), assessment of the major cognitive domains, and potential to detect subtle cognitive impairment in PD. Five scales of global cognition met the predetermined screening criteria and were considered for review. Based on the Task Force's evaluation criteria the Montreal Cognitive Assessment (MoCA), appeared to be the most suitable measure. This Task Force recommends consideration of the MoCA as a minimum cognitive screening measure in clinical trials of PD where cognitive performance is not the primary outcome measure. The MoCA still requires further study of its diagnostic utility in PD populations but appears to be the most appropriate measure among the currently available brief cognitive assessments. Widespread adoption of a single instrument such as the MoCA in clinical trials can improve comparability between research studies on PD. © 2010 Movement Disorder Society

Url:

DOI: 10.1002/mds.23362

Affiliations:

Canada, États-Unis
Californie, Caroline du Nord, Floride, Illinois, Iowa, Kentucky, Maryland, Massachusetts, Michigan, Pennsylvanie, Texas
Iowa City
Université de l'Iowa

Le document en format XML

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<author><name sortKey="Litvan, Irene" sort="Litvan, Irene" uniqKey="Litvan I" first="Irene" last="Litvan">Irene Litvan</name>
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<term>Cognition Disorders (diagnosis)</term>
<term>Cognition Disorders (psychology)</term>
<term>Cognitive disorder</term>
<term>Humans</term>
<term>Medical screening</term>
<term>Nervous system diseases</term>
<term>Neuropsychological Tests</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (psychology)</term>
<term>Parkinson disease</term>
<term>Parkinson's disease</term>
<term>Psychometrics</term>
<term>Questionnaires</term>
<term>cognitive impairment</term>
<term>cognitive screening</term>
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<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Cognition Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Cognition Disorders</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Clinical Trials as Topic</term>
<term>Cognition</term>
<term>Humans</term>
<term>Neuropsychological Tests</term>
<term>Psychometrics</term>
<term>Questionnaires</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Dépistage</term>
<term>Essai clinique</term>
<term>Maladie de Parkinson</term>
<term>Pathologie du   système nerveux</term>
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<front><div type="abstract" xml:lang="en">Cognitive impairment is common in Parkinson's disease (PD). There is a critical need for a brief, standard cognitive screening measure for use in PD trials whose primary focus is not on cognition. The Parkinson Study Group (PSG) Cognitive/Psychiatric Working Group formed a Task Force to make recommendations for a cognitive scale that could screen for dementia and mild cognitive impairment in clinical trials of PD where cognition is not the primary outcome. This Task Force conducted a systematic literature search for cognitive assessments previously used in a PD population. Scales were then evaluated for their appropriateness to screen for cognitive deficits in clinical trials, including brief administration time (<15 minutes), assessment of the major cognitive domains, and potential to detect subtle cognitive impairment in PD. Five scales of global cognition met the predetermined screening criteria and were considered for review. Based on the Task Force's evaluation criteria the Montreal Cognitive Assessment (MoCA), appeared to be the most suitable measure. This Task Force recommends consideration of the MoCA as a minimum cognitive screening measure in clinical trials of PD where cognitive performance is not the primary outcome measure. The MoCA still requires further study of its diagnostic utility in PD populations but appears to be the most appropriate measure among the currently available brief cognitive assessments. Widespread adoption of a single instrument such as the MoCA in clinical trials can improve comparability between research studies on PD. © 2010 Movement Disorder Society</div>
</front>
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Movement Disorders (revue)

A recommended scale for cognitive screening in clinical trials of Parkinson's disease

A recommended scale for cognitive screening in clinical trials of Parkinson's disease

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Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
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